Biomimetic Design and Fabrication of Interior Architecture of Tissue Scaffolds Using Solid Freeform Fabrication

Modeling, design and fabrication of tissue scaffolds with intricate architecture, porosity and pore size for desired tissue properties presents a challenge in tissue engineering. This paper will present the details of our development in designing and fabrication of the interior architecture of scaffolds using a novel design approach. The Interior Architecture Design (IAD) approach seeks to generate scaffold layered freeform fabrication tool path without forming complicated 3D CAD scaffold models. This involves: applying the principle of layered manufacturing to determine the scaffold individual layered process planes and layered contour; defining the 2D characteristic patterns of the scaffold building blocks (unit cells) to form the Interior Scaffold Pattern; and the generation of process tool path for freeform fabrication of these scaffolds with the specified interior architecture. Feasibility studies applying the IAD algorithm to example models and the generation of fabrication planning instructions will be presented.Mechanical Engineerin

Effect of the foam embellishments on the pedestrian safety of the vehicle front protection systems

Pedestrian safety related compliance requirements are very important in case of design and development of the vehicle front protection systems. Computer aided engineering impact simulations were carried out to evaluate Head Injury Criterion (HIC) of a typical bullbar impacting it with an adult headform and correlated with experimental results. Impact simulations were carried out on the same bullbar covered with semi‐rigid polyurethane foam to study the effect of foam embellishments on the pedestrian safety. Results obtained from the impact simulations were presented in this paper

Phase Transitions in Lyotropic Nematic Gels

In this paper, we discuss the equilibrium phases and collapse transitions of a lyotropic nematic gel immersed in an isotropic solvent. A nematic gel consists of a cross-linked polymer network with rod-like molecules embedded in it. Upon decreasing the quality of the solvent, we find that a lyotropic nematic gel undergoes a discontinuous volume change accompanied by an isotropic-nematic transition. We also present phase diagrams that these systems may exhibit. In particular, we show that coexistence of two isotropic phases, of two nematic phases, or of an isotropic and a nematic phase can occur.Comment: 13 pages Revtex, 10 figures, submitted to EPJ

FIR Filter Implementation by Efficient Sharing of Horizontal and Vertical Common Sub-expressions

No abstract availabl

Combining Thesaurus Knowledge and Probabilistic Topic Models

In this paper we present the approach of introducing thesaurus knowledge into probabilistic topic models. The main idea of the approach is based on the assumption that the frequencies of semantically related words and phrases, which are met in the same texts, should be enhanced: this action leads to their larger contribution into topics found in these texts. We have conducted experiments with several thesauri and found that for improving topic models, it is useful to utilize domain-specific knowledge. If a general thesaurus, such as WordNet, is used, the thesaurus-based improvement of topic models can be achieved with excluding hyponymy relations in combined topic models.Comment: Accepted to AIST-2017 conference (http://aistconf.ru/). The final publication will be available at link.springer.co

Electronic ground states of Fe2+_2^+ and Co2+_2^+ as determined by x-ray absorption and x-ray magnetic circular dichroism spectroscopy

The $^6\Pi$ electronic ground state of the Co$_2^+$ diatomic molecular cation has been assigned experimentally by x-ray absorption and x-ray magnetic circular dichroism spectroscopy in a cryogenic ion trap. Three candidates, $^6\Phi$, $^8\Phi$, and $^8\Gamma$, for the electronic ground state of Fe$_2^+$ have been identified. These states carry sizable orbital angular momenta that disagree with theoretical predictions from multireference configuration interaction and density functional theory. Our results show that the ground states of neutral and cationic diatomic molecules of $3d$ transition elements cannot generally be assumed to be connected by a one-electron process

Quantifying properties of ICM inhomogeneities

We present a new method to identify and characterize the structure of the intracluster medium (ICM) in simulated galaxy clusters. The method uses the median of gas properties, such as density and pressure, which we show to be very robust to the presence of gas inhomogeneities. In particular, we show that the radial profiles of median gas properties are smooth and do not exhibit fluctuations at locations of massive clumps in contrast to mean and mode properties. It is shown that distribution of gas properties in a given radial shell can be well described by a log-normal PDF and a tail. The former corresponds to a nearly hydrostatic bulk component, accounting for ~99% of the volume, while the tail corresponds to high density inhomogeneities. We show that this results in a simple and robust separation of the diffuse and clumpy components of the ICM. The FWHM of the density distribution grows with radius and varies from ~0.15 dex in cluster centre to ~0.5 dex at 2r_500 in relaxed clusters. The small scatter in the width between relaxed clusters suggests that the degree of inhomogeneity is a robust characteristic of the ICM. It broadly agrees with the amplitude of density perturbations in the Coma cluster. We discuss the origin of ICM density variations in spherical shells and show that less than 20% of the width can be attributed to the triaxiality of the cluster gravitational potential. As a link to X-ray observations of real clusters we evaluated the ICM clumping factor with and without high density inhomogeneities. We argue that these two cases represent upper and lower limits on the departure of the observed X-ray emissivity from the median value. We find that the typical value of the clumping factor in the bulk component of relaxed clusters varies from ~1.1-1.2 at r_500 up to ~1.3-1.4 at r_200, in broad agreement with recent observations.Comment: 16 pages, 12 figure, accepted to MNRA

Structural evaluation of concrete expanded polystyrene sandwich panels for slab applications

Sandwich panels are being extensively and increasingly used in building construction because they are light in weight, energy efficient, aesthetically attractive and can be easily handled and erected. This paper presents a structural evaluation of Concrete-Expanded Polystyrene (CEPS) sandwich panels for slab applications using finite element modeling approach. CEPS panels are made of expanded polystyrene foam sandwiched between concrete skins. The use of foam in the middle of sandwich panel reduces the weight of the structure and also acts as insulation against thermal, acoustics and vibration. Applying reinforced concrete skin to both sides of panel takes the advantages of the sandwich concept where the reinforced concrete skins take compressive and tensile loads resulting in higher stiffness and strength and the core transfers shear loads between the faces. This research uses structural software Strand7, which is based on finite element method, to predict the load deformation behaviour of the CEPS sandwich slab panels. Non linear static analysis was used in the numerical investigations. Predicted results were compared with the existing experimental results to validate the numerical approach used

Direct Slicing of STEP Based NURBS Models for Solid Freeform Fabrication

Direct slicing of CAD models to generate process planning instructions for solid freeform fabrication may overcome inherent disadvantages of using STL format in terms of the process accuracy, ease of file management, and incorporation of multiple materials. This paper will present the results of our development of a direct slicing algorithm for layered freeform fabrication. The direct slicing algorithm was based on a neutral, international standard (ISO 10303) STEP-formatted NURBS geometric representation and is intended to be independent of any commercial CAD software. The following aspects of the development effort will be presented: 1) Determination of optimal build direction based upon STEP-based NURBS models; 2) Adaptive subdivision of NURBS data for geometric refinement; and 3) Ray-casting slice generation into sets of raster patterns. Feasibility studies applying the direct slicing algorithm to example models and the generation of fabrication planning instructions involving multi-material structures will also be presented.Mechanical Engineerin